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dc.contributor.authorPandey, Saumya-
dc.contributor.authorJahageerdar, Shrinivas-
dc.identifier.issn0975-1084 (Online); 0022-4456 (Print)-
dc.description.abstractIn ornamental fisheries, body ornamentation, including the body colour, is of great economic importance. Melanocortin-1 receptor (MC1R) gene is primarily responsible for pigmentation in the majority of the vertebrates, and its modulation will help to understand the pigmentation and external body coloration. The present study was aimed to predict the MC1R tertiary protein structure of Tetraodon nigroviridis through homology modelling and to identify putative modulators. The tertiary protein structure of the MC1R protein of T. nigroviridis was homology modelled and validated. BLAHtetrone with binding efficiency of -9.7 kcal/mol was identified as a putative modulator of the MC1R protein.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceJSIR Vol.79(08) [August 2020]en_US
dc.subjectG-protein coupled receptoren_US
dc.subjectHomology modelingen_US
dc.subjectVirtual screeningen_US
dc.titleComputational Modelling of Tetraodon nigroviridis Melanocortin-1 Receptor (MC1R) Protein and Identification of Natural Compounds as Putative Modulatorsen_US
Appears in Collections:JSIR Vol.79(08) [August 2020]

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