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Title: Effect of <i style="">Curcuma longa</i> or parziquantel on <i style="">Schistosoma mansoni</i> infected mice liver — Histological and histochemical study
Authors: El-Banhawey, Mahmoud A
Ashry, Madeha A.
EL-Ansary, Afaf K.
Aly, Sanaa A.
Keywords: Acid phosphatase
Alkaline phosphatase
<i style="">Curcuma longa</i>
S<i style="">chistosoma mansoni</i>
Issue Date: Oct-2007
Publisher: CSIR
Abstract: Effect of drug praziquantel (PZQ) and <i style="">C. longa</i> extract on <i style="">S. mansoni</i> infected mice is reported. The level of glycogen, alkaline and acid phosphatases (ALP and ACP respectively), and body weight, liver weight and liver weight/body weight ratio were studied in mice infected with <i style="">S.mansoni</i>. ALP level was increased after infection. <i style="">C. longa</i> treated mice showed marked reduction in ALP level more than after PZQ-treatment. <i style="">C. longa</i> enhanced the concentration of glycogen after being reduced by infection, while PZQ-treatment revealed more reduction. <i style="">C. longa</i> caused enhancement in body weight while PZQ treatment had no effect. The formation of granuloma around schistosome eggs in the liver produced inflammation. <i style="">C.longa </i>extract and PZQ were effective in reducing granuloma size in infected mice.
Description: 877-889
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.45(10) [October 2007]

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