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Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.45 [2007] >
IJEB Vol.45(04) [April 2007] >
| Title: | Dietary fish oil as hepatoprotective agent in Mus musculus |
| Authors: | Roy, R
Chandrasekhar, D
Pujari, P |
| Keywords: | Cirrhosis
Fish-oil
Galactosamine
PUFA |
| Issue Date: | Apr-2007 |
| Publisher: | CSIR |
| Abstract: | The administration of galactosamine in omega-3 polyunsatu-rated fatty acid (PUFA) supplemented mice resulted in lesser amount of damage in the liver tissue compared to the mice without prior supplementation of fish oil. Only 50% elevation in the plasma total bilirubin was detected in omega-3 supplemented mice injected with galactosamine over those supplemented with omega-3 without galactosomine injection. The results suggest that very long chain omega-3 PUFA like eicosapentaenoic and docosahexaenoic acid may act as preventive agent for hepatic cirrhosis in Mus musculus. |
| Page(s): | 367-370 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.45(04) [April 2007]
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