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Title: Dietary fish oil as hepatoprotective agent in Mus musculus
Authors: Roy, R
Chandrasekhar, D
Pujari, P
Keywords: Cirrhosis;Fish-oil;Galactosamine;PUFA
Issue Date: Apr-2007
Publisher: CSIR
Abstract: The administration of galactosamine in omega-3 polyunsatu-rated fatty acid (PUFA) supplemented mice resulted in lesser amount of damage in the liver tissue compared to the mice without prior supplementation of fish oil. Only 50% elevation in the plasma total bilirubin was detected in omega-3 supplemented mice injected with galactosamine over those supplemented with omega-3 without galactosomine injection. The results suggest that very long chain omega-3 PUFA like eicosapentaenoic and docosahexaenoic acid may act as preventive agent for hepatic cirrhosis in Mus musculus.
Page(s): 367-370
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.45(04) [April 2007]

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