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IJEB Vol.45(09) [September 2007] >


Title: Hypoglycemic and hypolipidemic effects of alcoholic extract of Tribulus alatus in streptozotocin-induced diabetic rats: A comparative study with T. terrestris (Caltrop)
Authors: El-Tantawy, W H
Hassanin, L A
Keywords: Alcoholic extract
Diabetic rats
Hypoglycemic
Hypolipidemic
Tribulus alatus
Tribulus terrestris
Issue Date: Sep-2007
Publisher: CSIR
Abstract: The extracts of both T. alatus and T. terrestris significantly decrease fasting glucose level in diabetic rats. After 4 and 6 hr, T. alatus extract showed significant reduction in glucose level as compared to T. terrestris. After 3 weeks of treatment with T. alatus extract, glucose level was significantly decreased to the normal level. Both the extracts also caused a significant decrease in the levels of glycosylated hemoglobin, total cholesterol, triglycerides and LDL-cholesterol. The percent of reduction in rats treated with T. alatus extract was significantly higher than that of the rats treated with T. terrestris. The results indicate that alcoholic extract of T. alatus possesses hypoglycemic activity in type-1 model of diabetes.
Page(s): 785-790
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.45(09) [September 2007]

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