Please use this identifier to cite or link to this item:
Title: Zinc dust catalysed efficient synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones
Authors: Hiremath, Prashant B
Kantharaju, K
Keywords: Oxazolones;Hippuric acid;Aldehyde;Zinc dust;Mild condition
Issue Date: Jul-2020
Publisher: NISCAIR-CSIR, India
Abstract: A straight forward synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones (also called azlactones) by the condensation of arylaldehyde with hippuric acid in the presence of acetic anhydride and zinc dust as aheterogeneous catalyst is described. The reaction proceeds rapidly, does not require any additives and has a significantly shorter reaction rate. In the present method, aromatic aldehydes and hippuric acid have been successfully applied to synthesize various substituted azlactones in good to excellent yields. The final product has been characterised by FT-IR, 1H and 13C NMR, and mass spectrometry.
Page(s): 1010-1015
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.59B(07) [July 2020]

Files in This Item:
File Description SizeFormat 
IJCB 59B(7) 1010-1015.pdfMain Article153.42 kBAdobe PDFView/Open
IJCB 59B(7) 1010-1015_Suppl Data.pdfSupplementary Data684.49 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.