Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/54407
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dc.contributor.authorPrasoona, G-
dc.contributor.authorKishore, B-
dc.contributor.authorBrahmeshwari, G-
dc.date.accessioned2020-05-20T06:26:15Z-
dc.date.available2020-05-20T06:26:15Z-
dc.date.issued2020-04-
dc.identifier.issn0975-0983(Online); 0376-4699(Print)-
dc.identifier.urihttp://nopr.niscair.res.in/handle/123456789/54407-
dc.description445-453en_US
dc.description.abstractSynthesis of novel benzo[4,5]imidazo[1,2-a]pyrimido[4,5-d] pyrimidines 5/6 has been achieved by reaction of 2-amino-4-aryl-4,10-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-3-carbonitriles 4 with formaldehyde/urea. The key intermediate 4, is obtained by reaction of 2-aminobenzaldehyde 1 with aromatic aldehyde and malononitrile by a three-component one-pot process. The newly synthesized title compounds 5/6 have been evaluated for their in vitro antimicrobial activity. Compounds 5 and 6 exhibit potent antimicrobial activity compared to that of standard drugs.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-B Vol.59B(04) [April 2020]en_US
dc.subjectMulti-component reactionen_US
dc.subjectBenzo[4,5]imidazo[1,2-a]pyrimidine-3-carbonitrilesen_US
dc.subjectCyclizationen_US
dc.subjectBenzo[4,5]imidazo[1,2-a]pyrimido[4,5-d]pyrimidinesen_US
dc.subjectAntimicrobial activityen_US
dc.titleSynthesis of novel benzo[4,5]imidazo[1,2-a]pyrimido- [4,5-d]pyrimidine derivatives as potent antimicrobial agentsen_US
dc.typeArticleen_US
Appears in Collections:IJC-B Vol.59B(04) [April 2020]

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