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Title: Antioxidant and antimicrobial capacity of Lactifluus rugatus and its antiproliferative activity on A549 cells
Authors: SEVINDIK, Mustafa
Keywords: Antimicrobial;Antioxidant;Antiproliferative;Edible mushroom;Lactifluus rugatus;Oxidant
Issue Date: Apr-2020
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl.20: A41D 31/30, A61P 17/18, A61K 38/00, A23B 9/00, A61K 38/56
Abstract: In the present study, the antioxidant, antimicrobial potential and antiproliferative activity of Lactifluus rugatus mushroom were determined. Thus, extracts of the mushroom were obtained using a Soxhlet device. Antioxidant and oxidant potentials were determined using Rel Assay kits. Antimicrobial potential was tested on 9 microorganisms using the modified agar dilution method. MTT test was conducted on A549 cells to determine the anti-proliferative activity. As a result, high level of antioxidant activity was determined in L. rugatus. Furthermore, it was determined that the mushroom had antimicrobial properties on tested bacteria and fungi and strong anti-proliferative activity on A549 cells. In conclusion, it was considered that L. rugatus had pharmacological potential and it can be utilized as a natural pharmacological agent.
Page(s): 423-427
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.19(2) [April 2020]

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