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Title: Studies on artemisinin, morphotypic and genetic characteristics of seventeen species of Artemisia growing in Indian Himalayan Region
Authors: Paul, Shilpi
Sekar, K Chandra
Singh, Gopal
Pandey, Aseesh
Bisht, Monisha
Keywords: Artemisia species;Artemisinin pathway genes;Artemisinin;Genetic diversity;Phenotypic diversity
Issue Date: Dec-2019
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2015.01)-A61K 36/00, A61K 36/28, A61K 36/282, C11B 9/00
Abstract: Seventeen species of Artemisia L. growing in the Indian Himalayan region were investigated for artemisinin content, morphological and genetic characters. During the investigation, artemisinin content was found to be in the range of trace to 0.12%. The highest was in A. dracunculus (0.12%) and A. roxburghiana (0.12%). The essential oil content was found in the range of 0.03-1.5%, A. dracunculus showed 1.5% oil (w/v) followed by A. nilagirica (0.6%) and A. maritima (0.6%). The AFLP analysis revealed 25.4% (Hind-ACC & Mse-CAC) to 67.38% (Hind-ACA & Mse-CAG) polymorphism while overall it was 51%. The dendrogram generated from AFLP data classified 8 species in one cluster (I) and 9 in another (II). The important pathway genes (HMGR, ADS and CYP71AV1) showed higher expression in A. dracunculus, A. roxburghiana and A. sieversiana. Based on the chemical analysis, the presence of a high amount of essential oil and artemisinin in A. dracunculus and A. roxburghiana suggested that these could be important medicinal plants for future research.
Page(s): 272-279
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.10(4) [December 2019]

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