NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.47 [2009] >
IJEB Vol.47(08) [August 2009] >


Title: Immunomodulatory activity of aqueous extract of Achillea wilhelmsii C. Koch in mice
Authors: Sharififar, Fariba
Pournourmohammadi, Shirin
Arabnejad, Moslem
Keywords: Achillea wilhelmsii
DTH
Haemagglutination titre
Immunity response
Toxicity
Issue Date: Aug-2009
Publisher: CSIR
Abstract: Immunomodulatory activity of aqueous extract of Achillea wilhelmsii (25, 50 and 100 mg/kg body weight for 5 days) was evaluated on body weight, relative organ weight, delayed type of hypersensitivity (DTH) response and haemagglutination titre (HT) in female Swiss albino mice. No significant body weight gain differences were recorded in various groups of animals. Significant increase in relative organ weight of spleen at 100 mg/kg was observed. No elevation in the levels of liver function test (LFT) enzymes and kidney relative weight was observed in tested doses of the plant. The extract of A. wilhelmsii elicited a significant increase in the DTH response at the dose of 100 mg/kg. In the HT test, plant extract showed stimulatory effect in all doses, however this changes were significant at 50 mg/kg. No mortality was occurred in tested doses. Overall, A. wilhelmsii showed a stimulatory effect on both humoral and cellular immune functions in mice.
Page(s): 668-671
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.47(08) [August 2009]

Files in This Item:

File Description SizeFormat
IJEB 47(8) 668-671.pdf112.28 kBAdobe PDFView/Open
 Current Page Visits: 841 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 557664 since 06-Feb-2009  Last updated on 15-Jul-2014Webmaster: nopr@niscair.res.in