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Title: In-Vitro Evaluation of Anti-Inflammatory and Anti-Microbial Properties of Ethanolic Extract of Cydonia Oblonga Seeds
Authors: Shaida, Bushra
Singh, N B
Singh, Karuna
Keywords: Cydonia oblonga;Anti-oxidant;Anti-inflammatory;Antimicrobial;Minimum Inhibitory concentration (MIC)
Issue Date: Jan-2020
Publisher: NISCAIR-CSIR, India
Abstract: Phytochemical, antimicrobial, antioxidant and anti-inflammatory properties of ethanol extract of Cydonia oblonga were studied. The antioxidant and anti-inflammatory efficacy of the extract was assessed through different methods using DPPH and bovine albumin respectively. Total phenolic content (TPC) was estimated using Folin-Cioucalteu reagent. Antimicrobial effect of seeds was studied using disc diffusion method against gram positive and negative bacteria viz; S.aureus, P.aeruginosa and fungi C. albicans. Phyto-chemical analysis showed the presence of alkaloids, phenols, tannins, amino acids, carbohydrate, fats/oils and glycosides. TPC of the seed extract was found to be 37.46±0.10 mg GAE/gm, extract also showed significant antioxidant and anti-inflammatory activity with IC50 value of 299.98µg/ml and 300µg/ml respectively. Anti-microbial results indicated that Cydonia oblonga seeds extract is effective against gram positive bacteria.
Page(s): 49-52
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Appears in Collections:JSIR Vol.79(01) [January 2020]

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