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dc.contributor.authorSuresh, E.-
dc.contributor.authorSureshkumar, P.-
dc.identifier.issn0975-1033 (Online); 0379-5136 (Print)-
dc.description.abstractMilkweed or Calotropis gigantea belongs to Asclepiadaceae family having many curative principles in it. This present work aimed to study the phytochemicals prevailing in the Calotropis gigantea during the summer season by GCMS method and some of these phytochemicals tested against the collagen-binding matrix protein (4CN8) produced by the bacterial foulant through computational method. The result of GCMS analysis revealed that the prevalence of stigmasterol, alpha-amyrin, urs-12-en-24-oic acid, 3-oxo-, methyl ester, (+)-, 2(1H) Naphthalenone, 3,5,6,7,8, 8a-hexahydro-4, 8a-dimethyl-6-(1-ethylethenyl)-, Beta.-Amyrin, Bicyclo [3.1.1] heptane,2,6,6-trimethyl-, 1R-(1.alpha., 2.beta., 5.alpha.) -and 1H-Indene, 5-butyl-6-hexyloctahydro-, 2-[3-(4-tert-Butyl-phenoxy)-2-hydroxy-propylsulfanyl]-4,6-dimethyl-nicotinonitrile and cyclopropane carboxamide, 2-cyclopropyl-2-methyl-N-(1-cyclopropylethyl)- and pyridine-3-carboxamide, oxime, N-(2-trifluoro methyl phenyl). The in silico study exhibited that all the screened phytochemicals are having remarkably good interaction with the tested 4CN8 and possessing-8 to-11 Kcal/mol docking energy except pyridine-3-carboxamide, oxime, N-(2-trifluoromethylphenyl). Hence, the phytochemicals of Calotropis is a right candidate for further elaborate study to establish an eco-friendly alternative to existing toxic antifouling chemicals.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJMS Vol.48(12) [December 2019]en_US
dc.subjectCalotropis giganteaen_US
dc.subjectIn silicoen_US
dc.titleAntimicrofouling activity of Calotropis gigantea (L). R. Br.en_US
Appears in Collections:IJMS Vol.48(12) [December 2019]

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