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Title: Comparative study of the production of coumarins and furanocoumarins in three Ruteae species
Authors: Bergheul, Saida
Limones-Méndez, Mariana
Grosjean, Jérémy
Hehn, Alain
Olry, Alexandre
Berkani, Abdellah
Keywords: Coumarins;Furanocoumarins;Haplophyllum tuberculatum (Forsk.) Juss;Ruta angustifolia Pers;Ruta chalepensis L.;UHPLC-MS
Issue Date: Jun-2019
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2015.01)-A61K 36/00, A61K 36/75
Abstract: Within specialized metabolites, coumarins and furanocoumarins represent a wide group of structurally diverse compounds and are specially produced in plants belonging to the Rutaceae family. Here we performed the furanocoumarin and coumarin-targeted chemical characterization of three Ruteae species collected from Algeria. Detection and quantification of 27 coumarins and furanocoumarins extracted from stems and leaves was carried out by UHPLC-MS. We highlighted significant chemical differences between these plants. Ruta chalepensis L. is the highest producer with 24.83 mmol/g dry material in stems and 15.70 mmol/g dry materials in leaves while Haplophyllum tuberculatum (Forsk.) is the lowest producer. We also showed a surprising chemical diversity between R. chalepensis L and R. angustifolia Pers. This chemical diversity might, therefore, be a helpful tool for phylogenetic identification of plants.
Page(s): 137-142
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.10(2) [June 2019]

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