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Title: Synthesis, spectral characterization and bioactivity evaluation of sulfonamide derivatives of p-nitrobenzene sulfonylchloride
Authors: Ramudu, D B Janaki
Subramanyam, C H
Rasool, S K Nayab
Murthy, P Seenivasa
Devamma, M Nagalakshmi
Venkataramaiah, C H
Rajendra, W
Raju, Chamarthi Naga
Chalapathi, Ponne Venkata
Keywords: Sulfonamide;p-nitrobenzene sulfonylchloride;Streptomycin;Nystatin;Anti-microbial agents
Issue Date: Dec-2019
Publisher: NISCAIR-CSIR, India
Abstract: A simple and convenient method for the synthesis of biologically active sulfonamide derivatives of p-nitrobenzene sulfonylchloride has been achieved. All the title compounds have been characterized by spectral and elemental analysis. They have been further screened in┬ávitro for their antibacterial and antifungal activities. All the compounds show good to moderate activity against both bacteria and fungi when compared with standard bactericide, Streptomycin and fungicide, Nystatin.
Page(s): 1375-1383
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.58B(12) December 2019]

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