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|Title:||Inhibition of selenium dependent glutathione peroxidase and superoxide dismutase in rats by diethyldithiocarbamate: Effect of pre-administration of -tocopherol|
|Authors:||Prabhu, H Ramachandra|
|Keywords:||Diethyldithiocarbamate;Selenium dependent glutathione peroxidase;Superoxide dismutase;-tocopherol|
|Abstract:||Rats pre-administered with -tocopherol (10 mgs/day) for 7 days afforded a significant protection at the tissue level against the lowering of superoxide dismutase and glutathione peroxidase, especially the selenium-dependent glutathione peroxidase. The protective action of -tocopherol in the diethyldithiocarbamate treated rats may be attributed to its antioxidant/free radical scavenging action. It is concluded that selenium-dependent glutathione peroxidase and -tocopherol act in a complementary fashion to block free radical formation.|
|ISSN:||0975-1009 (Online); 0019-5189 (Print)|
|Appears in Collections:||IJEB Vol.45(05) [May 2007]|
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