| Abstract: | Treatment of 1,4-diazacyclohexan-2,5-dione 1 with bromine in carbon tetrachloride has yielded 1,4-diaza-3-bromo-2,5-dioxocyclohexane 2 and 1,4-diaza-3,3-dibromocyclohexane-2,5-dione 7. The reaction of 2 with carbamides/thiocarbamides has produced 6-oxo-oxazolo[4,5-b] piperazine 5 /2-substituted imino-6-oxo-thiazolo[4,5-b] piperazine 6. Compound 7 on combination with carbamides/ thiocarbamides is transformed to 1-oxo-2-substituted imino-3,5,8-triaza-3H,5H,8H,7-dihydro-6,9-dioxo-spiro [3.5] nonane 9 and 1-thia-2-substituted imino-3,5,8-triaza-3H,5H,8H-7dihydro-6,9-dioxo-spiro [3.5] nonane 9. The structures of the synthesized compounds have been confirmed by IR, 1H and 13C NMR spectral data analyses. |
