NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(07) [July 2009] >

Title: Synthetic studies towards steroid-amino acid hybrids
Authors: Shagufta
Singh, Ritesh
Panda, Gautam
Keywords: Steroid
amino acids
Yamaguchi coupling
Issue Date: Jul-2009
Publisher: CSIR
Abstract: New prototype of natural steroid amino acid hybrid containing nine membered D-ring in the steroid skeleton has been synthesized from commercially available estrone using standard synthetic organic transformations. NaIO4 cleavage of the D-ring of the benzylated estriol furnishes the D-seco diol 8, which after a series of organic reactions (protection of the hydroxyl group, oxidation, reductive amination, deprotection and the Yamaguchi cross coupling) gives the coveted steroid-amino acid hybrids. The methodology can be extended for combinatorial synthesis of new and interesting steroid amino acid hybrids.
Page(s): 989-995
ISSN: 0975-0983 (Online); 0376-4699 (Print)
Source:IJC-B Vol.48B(07) [July 2009]

Files in This Item:

File Description SizeFormat
IJCB 48B(7) 989-995.pdf150.09 kBAdobe PDFView/Open
 Current Page Visits: 11 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 23371 since 01-Sep-2015  Last updated on 13-Oct-2015Webmaster: