Please use this identifier to cite or link to this item:
|Title:||Stability and flow behaviour of barium sulphate suspension and the preparation of stable barium sulphate suspension for medical use|
|Keywords:||Barium sulphate suspension;Additives;Sodium carboxy methyl cellulose;Trisodium citrate;Viscosity;Rheogram template;Adsorption studies;Stability of suspension and Gastrointestinal tract;X-ray studies|
|IPC Code:||A 61 K 49/00|
|Abstract:||Stability and flow behaviour of concentrated barium sulphate suspension (BSS) was studied in the presence of sodium carboxy methyl cellulose (NaCMC), bentonite and poly vinyl pyrrolidone (PVP). NaCMC (0.2 %) showed maximum viscosity (50 %), maximum sedimentation volume of BSS and maximum (0.4 %) adsorption of NaCMC by BSS. Bentonite and PVP had no significant effect on sedimentation volume of BSS but increased the viscosity . The radiological studies on the X-ray picture of rabbit using BSS (50 %) and NaCMC (0.2 %) exhibited poor contrast of the stomach region. To increase the stability, suspension was mixed with tri sodium citrate (4 %). The X-ray picture of rabbit showed good contrast of the stomach as well as the small intestine region.|
|ISSN:||0975-1084 (Online); 0022-4456 (Print)|
|Appears in Collections:||JSIR Vol.64(04) [April 2005]|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.