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Title: | Stability and flow behaviour of barium sulphate suspension and the preparation of stable barium sulphate suspension for medical use |
Authors: | Nag, Ahindra |
Keywords: | Barium sulphate suspension;Additives;Sodium carboxy methyl cellulose;Trisodium citrate;Viscosity;Rheogram template;Adsorption studies;Stability of suspension and Gastrointestinal tract;X-ray studies |
Issue Date: | Apr-2005 |
Publisher: | CSIR |
IPC Code: | A 61 K 49/00 |
Abstract: | Stability and flow behaviour of concentrated barium sulphate suspension (BSS) was studied in the presence of sodium carboxy methyl cellulose (NaCMC), bentonite and poly vinyl pyrrolidone (PVP). NaCMC (0.2 %) showed maximum viscosity (50 %), maximum sedimentation volume of BSS and maximum (0.4 %) adsorption of NaCMC by BSS. Bentonite and PVP had no significant effect on sedimentation volume of BSS but increased the viscosity . The radiological studies on the X-ray picture of rabbit using BSS (50 %) and NaCMC (0.2 %) exhibited poor contrast of the stomach region. To increase the stability, suspension was mixed with tri sodium citrate (4 %). The X-ray picture of rabbit showed good contrast of the stomach as well as the small intestine region. |
Page(s): | 268-272 |
URI: | http://hdl.handle.net/123456789/5133 |
ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
Appears in Collections: | JSIR Vol.64(04) [April 2005] |
Files in This Item:
File | Description | Size | Format | |
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JSIR 64(4) 268-272.pdf | 265.48 kB | Adobe PDF | View/Open |
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