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Title: Clinical trial of Unani herbomineral cream to evaluate its topical effects on Acne vulgaris
Authors: Parveen, Shagufta
Zafar, Sharique
Qureshi, Masroor Ali
Bano, Humaira
Keywords: Unani medicine
Acne vulgaris
Unani herbomineral cream
Issue Date: Jul-2009
Publisher: CSIR
IPC CodeInt. Cl.8: A61K36/00, A61P17/00, A61P17/10
Abstract: A controlled, randomized single blind clinical trial was conducted as per GCP guidelines for the duration of 2 months on the human individuals suffering from acne vulgaris. The patients were divided into 2 groups, control group treated topically with only cream base and the test group treated topically with the UHC. The effects of the Unani herbomineral cream (UHC) were scientifically evaluated in human beings in acne vulgaris. The assessment of the severity of acne vulgaris in the control and test groups was made by the Investigators Global Acne Severity Score. The statistical analysis of the results of severity of acne vulgaris in the control and test groups was made for the total duration of treatment. Group comparisons (within and inter group) were made using ANOVA and paired t- test respectively. The effect of only cream base did not show any significant improvement in the acne vulgaris of the patients of control group. On the other hand, the within group and inter group comparisons in the test group showed significant differences at each stage of the treatment. The test drug, UHC has been proved effective in the treatment of acne vulgaris in the test group in comparison to the control group.
Page(s): 431-436
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Source:IJTK Vol.08(3) [July 2009]

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