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Title: Therapeutic efficacy of <i style="">Agnimantha </i>(<i style="">Premna obtusifolia </i>R. Br.) in obesity (<i style="">Sthaulya</i>)
Authors: Ghosh, Rina
Ghosh, Sukumar
Maity, Lakshmi Narayan
Keywords: <i>Ayurvedic </i>drugs
<i>Premna</i> <i>obtusifolia</i>
Issue Date: Jul-2009
Publisher: CSIR
Series/Report no.: <b>Int. Cl.<sup>8</sup>: </b>A61K36/00, A61P3/04, A61P3/06
Abstract: <i style="">Sthaulya</i> is a deprecate state of human being. The physical morbidity of <i style="">Sthaulya</i> is paramount and enhances several disease processes. In the study, the role of <i style="">Agnimantha</i> (<i style="">Premna obtusifolia </i>R. Br.) as antiobesity agent has been studied in 26 subjects with severe form of <i style="">Sthaulya</i> and has been compared in 24 age and sex matched controlled subjects. Subjects of treatment showed remarkable decrease in BMI, triglyceride, cholesterol-HDL ratio, uric acid, LDL-HDL ratio and midtriceps skin-fold thickness. However, these observations are persistent only after continuation of treatment for 9 months. These observations could be more substantiated if a larger study is carried out with assessment of lipoprotein lipase activity and leptine determination. <i style="">Agnimantha</i> shows significant therapeutic value in obesity. The drug being <i style="">tikta-katu rasa, ruksha-laghu guna, ushna virya, Katu-vipaka</i>, act nicely for the treatment of obesity. <i style="">Agnimantha</i> is an ideal drug for the treatment of obesity as it is potent, innocent, cheap and easily available.
Description: 369-371
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.08(3) [July 2009]

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