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|Title:||Preparation and characterization of a mercury based Indian traditional drug — <i style="">Ras-Sindoor</i>|
|Authors:||Singh, Sunil Kumar|
|Series/Report no.:||<b>Int. Cl.<sup>8</sup>: </b>A61K36/00, A61P15/00, A61P15/02, A61P31/00, A61P31/04|
|Abstract:||The mercury based Indian traditional drug<b style=""> </b>Ras-Sindoor<b style=""> </b>is administered for the various ailments such as syphilis, genital disorders, and for rejuvenation. Pharmaceutical processing of <i style="">Ras-Sindoor</i> involves treating metallic mercury with sulfur and the juice of the aerial root of Banyan tree<i style=""> (Ficus benghalensis </i>Linn.<i style="">)</i> and then controlled intermittent heating so that the metallic state is transformed into the corresponding sulfide form. In the study, synthesis and systematic characterization of this drug using various techniques, viz. X-ray diffraction (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), far infrared spectroscopy (FIR), Fourier transform infrared spectroscopy (FTIR), differential thermal analysis (DTA), thermogravimetry analysis (TGA), energy dispersive X-ray analysis (EDAX) and atomic absorption spectroscopy (AAS) have been reported. Drug contains mercury in the mercury sulfide form (Hg<sup>2+</sup>) being nanocrystalline (20-50 nm) in nature and associated with the organic contents of the aerial root of the <i style="">Ficus benghalensis </i>Linn. Some specific findings were also made which could be of help for the interpretation of therapeutic value, none-toxicity of <i style="">Ras-Sindoor</i> and for the standardization of such kind of traditional herbo-metallic drugs.|
|ISSN:||0975-1068 (Online); 0972-5938 (Print)|
|Appears in Collections:||IJTK Vol.08(3) [July 2009]|
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