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IJC-B Vol.46B(04) [April 2007] >


Title: Efficient synthesis of bis(indolyl) methanes in aqueous medium catalyzed by molybdenyl acetylacetonate
Authors: Banerjee, B
Mandal, S K
Roy, S C
Keywords: Bis(indolyl)methanes
Molybdenyl acetylacetonate
Aqueous medium
Carbonyl compounds
Catalysis
Issue Date: Apr-2007
Publisher: CSIR
IPC CodeInt. Cl.⁸ C07D
Abstract: A mild and efficient electrophilic substitution reaction of indoles with aldehydes and ketones has been carried out in water medium using a catalytic amount of MoO₂(acac)₂ to afford the corresponding bis(indolyl)methanes in excellent yields. Vibrindole A, a bacterial metabolite and biologically active 3,3'-diindolyl methane has been successfully synthesized in excellent yield using this methodology.
Page(s): 669-673
ISSN: 0376-4699
Source:IJC-B Vol.46B(04) [April 2007]

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