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Title: Fumaric acid catalyzed a green convenient and expedient approach for facile preparation of 3,4-dihydropyrimidin-2-(1H)-ones/thiones derivatives and N-aryl-3-aminodihydropyrrole-2-one-4-carboxylates under eco-safe conditions
Authors: Mohamadpour, Farzaneh
Keywords: Fumaric acid;3,4-dihydropyrimidinones/thiones;N-aryl-3- aminodihydropyrrol-2-one-4-carboxylates;Naturally green catalyst;Multi-component reactions;Green chemistry
Issue Date: Jul-2019
Publisher: NISCAIR-CSIR, India
Abstract: Fumaric acid as a naturally green and efficient catalyst has been found to be cost effective for the one-pot three-component Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones derivatives and one-pot four-component domino condensation of N-aryl-3-aminodihydropyrrol-2-one-4-carboxylates. Fumaric acid shows promising features for these reactions, such as eco-friendly, easily separation with no column chromatographic separation, clean synthesis, simple operational procedures, excellent yields and short reaction times.
Page(s): 820-831
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.58B(07) [July 2019]

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