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|Title:||Fumaric acid catalyzed a green convenient and expedient approach for facile preparation of 3,4-dihydropyrimidin-2-(1H)-ones/thiones derivatives and N-aryl-3-aminodihydropyrrole-2-one-4-carboxylates under eco-safe conditions|
|Keywords:||Fumaric acid;3,4-dihydropyrimidinones/thiones;N-aryl-3- aminodihydropyrrol-2-one-4-carboxylates;Naturally green catalyst;Multi-component reactions;Green chemistry|
|Abstract:||Fumaric acid as a naturally green and efficient catalyst has been found to be cost effective for the one-pot three-component Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones derivatives and one-pot four-component domino condensation of N-aryl-3-aminodihydropyrrol-2-one-4-carboxylates. Fumaric acid shows promising features for these reactions, such as eco-friendly, easily separation with no column chromatographic separation, clean synthesis, simple operational procedures, excellent yields and short reaction times.|
|Appears in Collections:||IJC-B Vol.58B(07) [July 2019]|
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