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Title: Synthesis and bioactivity study of 2,5-bismercapto-1,3,4- thiadiazole heterocyclic derivatives
Authors: Li, Man-Lin
Zhang, You-Ming
Wei, Tai-Bao
Keywords: 1,3,4-thiadiazole;Acylhydrazone;Thiosemicarbazide;Microwave irradiation
Issue Date: Mar-2007
Publisher: CSIR
IPC Code: Int.Cl.⁸C07D
Abstract: A series of acylhydrazone compounds 3a-i and acylthiosemicarbazides 4a-h containing thiadiazole rings have been synthesized conveniently in high yields. Some heterocyclic derivatives 5 are prepared by the method of dehydration of compounds 4. Structure of all these compounds have been confirmed by elemental analysis, IR, ¹H and ¹³C NMR. The bioassay result indicates that some compounds have relatively low antibacterial activity and other compounds have bioactivity for improving plant growth.
Page(s): 544-549
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.46B(03) [March 2007]

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