NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section A (IJC-A) >
IJC-A Vol.48A [2009] >
IJC-A Vol.48A(06) [June 2009] >


Title: Simultaneous kinetic determination of paracetamol and caffeine using Cu(II)-neocuproine in presence of dodecyl sulfate by H-point standard addition method
Authors: Tavallali, H
Sheikhaei, M
Keywords: Analytical chemistry
Spectrophotometry
H-point standard addition
Paracetamol
Caffeine
Neocuproine
Issue Date: Jun-2009
Publisher: CSIR
IPC CodeInt Cl.8 G01N21/25
Abstract: A simple, feasible and selective kinetic spectrophotometric method for simultaneous determination of paracetamol and caffeine using H-point standard addition method is described. The method is based on difference in the rate of oxidation of the compounds with Cu(II)-neocuproine system and formation of Cu(I)–neocuproine complex, which is monitored at 453 nm and at pH 5.0 in the presence of sodium dodecyl sulfate. Experimental conditions such as pH, reagents concentrations, ionic strength and temperature have been optimized. Paracetamol and caffeine can be determined in the range 1.5-7.0 and 0.1-3.0 μg ml-1 respectively. The proposed method has been applied for the determination of paracetamol and caffeine in pharmaceutical samples with satisfactory results.
Page(s): 812-816
ISSN: O975-0975 (Online); 0376-4710 (Print)
Source:IJC-A Vol.48A(06) [June 2009]

Files in This Item:

File Description SizeFormat
IJCA 48A(6) 812-816.pdf158.34 kBAdobe PDFView/Open
 Current Page Visits: 673 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 513360 since 06-Feb-2009  Last updated on 21-Apr-2014Webmaster: nopr@niscair.res.in