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Title: Effect of ripe fruit pulp extract of Cucurbita pepo Linn. in aspirin induced gastric and duodenal ulcer in rats
Authors: Sarkar, Sentu
Guha, Debjani
Keywords: Alkaline phosphatase;Aspirin;Cucurbita pepo;Gastric and Duodenal ulcer;Mucosal thickness;Ulcer index
Issue Date: Sep-2008
Publisher: CSIR
Abstract: A significant decrease in alkaline phosphatase (AP) activity and mucosal thickness and increase in ulcer index (UI) was observed in aspirin treated stomach and duodenum of albino rats. However, pretreatment with C. pepo fruit pulp extract for 14 consecutive days showed increase in AP activity and mucosal thickness along with decrease in UI, suggesting gastro-duodenal protective and anti-ulcerogenic properties of C. pepo.
Page(s): 639-645
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.46(09) [September 2008]

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