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Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.46 [2008] >
IJEB Vol.46(09) [September 2008] >
| Title: | Effect of ripe fruit pulp extract of Cucurbita pepo Linn. in aspirin induced gastric and duodenal ulcer in rats |
| Authors: | Sarkar, Sentu Guha, Debjani |
| Keywords: | Alkaline phosphatase Aspirin Cucurbita pepo Gastric and Duodenal ulcer Mucosal thickness Ulcer index |
| Issue Date: | Sep-2008 |
| Publisher: | CSIR |
| Abstract: | A significant decrease in alkaline phosphatase (AP) activity and mucosal thickness and increase in ulcer index (UI) was observed in aspirin treated stomach and duodenum of albino rats. However, pretreatment with C. pepo fruit pulp extract for 14 consecutive days showed increase in AP activity and mucosal thickness along with decrease in UI, suggesting gastro-duodenal protective and anti-ulcerogenic properties of C. pepo. |
| Page(s): | 639-645 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.46(09) [September 2008]
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