NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(03) [March 2007] >


Title: Novel one-pot synthesis of 1,3-dithiins and 1,3-thiazines under microwave irradiation
Authors: Siddiqui, Ibadur R
Singh, Pravin K
Keywords: Expedited
Dithiins
Thiazine
Knoevenagel condensation
Michael addition
Issue Date: Mar-2007
Publisher: CSIR
IPC CodeInt.Cl.⁸C07D
Abstract: A microwave induced expedited, high yielding three-component synthesis of 4,4'-bis[7''-aryl-5''- arylimino-2'',3'',5'',7''- tetrahydrothiazolo[4,5-d][1,3] dithiin-2''-thion-3"- yl)bibenzyls 3a-j and 4,4'-bis[4'',7''-diaryl -2'',3'',4'',5'',7''-pentahydrothiazolo [4,5-d][1,3]thiazine-2'',5''- dithion-3"-yl]bibenzyls 4a-j in one-pot involving Knoevenagel condensation followed by Michael addition is reported. The reaction is catalyzed by cheap and easily available NaCl under solvent-free conditions with excellent yield. The rate of the reaction has been found to be accelerated 213 fold as compared to the conventional method. The reaction is highly chemoselective and all the synthesized bibenzyl based 1,3-dithiins 3a-j and 1,3-thiazines 4a-j show promising antifungal activity.
Page(s): 499-504
ISSN: 0376-4699
Source:IJC-B Vol.46B(03) [March 2007]

Files in This Item:

File Description SizeFormat
IJCB 46B(3) (2007) 499-504.pdf203.83 kBAdobe PDFView/Open
 Current Page Visits: 552 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 588269 since 06-Feb-2009  Last updated on 18-Sep-2014Webmaster: nopr@niscair.res.in