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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(06) [June 2009] >
| Title: | Facile and efficient synthesis of 1,3,4-oxadiazolyl 1,8-naphthyridines under microwave irradiation |
| Authors: | Mogilaiah, K
Babu, H Sharath
Prasad, R Shiva |
| Keywords: | 1,8-Naphthyridines
1,3,4-oxadiazoles
iodobenzene diacetate [PhI(OAc)2]
microwave irradiation
solvent-free conditions |
| Issue Date: | Jun-2009 |
| Publisher: | CSIR |
| Abstract: | An efficient and convenient method for the synthesis of 1-(5-aryl-[1,3,4]-oxadiazol-2-ylmethyl)-3-(3-trifluromethylÂphenyl)-1H-[1,8]-naphthyridin-2-ones 5, by the oxidation of [2-oxo-3-(3-trifluoromethyl-phenyl)-2H-[1,8]naphthyridin-1-yl]acetic acid arylidenehydrazides 4 with iodobenzene diacetate [PhI(OAc)2] under microwave irradiation in solvent-free conditions, is described. The products are obtained in good yields and in a state of high purity. The structures of the synthesized compounds have been established on the basis of spectral and analytical data. |
| Page(s): | 868-872 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.48B(06) [June 2009]
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