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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(03) [March 2007] >
| Title: | Synthesis of 1-alkyl/aralkyl-2- (1-arylsulfonylalkyl) benzimidazoles under PTC conditions |
| Authors: | Dubey, P K
Reddy, P V V Prasada
Srinivas, K |
| Keywords: | 1-Substituted-2-(⍺–chloroalkyl)benzimidazole
Ar-SO₂- Na⁺
TEBAC
Sulphones |
| Issue Date: | Mar-2007 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl⁸ C07D |
| Abstract: | 2-(⍺-chloroalkyl)benzimidazoles 1 on reaction with arylsulphinate sodium salt 2, in CH₃CN under PTC conditions, gives 3 which on alkylation yields 1-alky/aralkyl-2-(⍺-aryl sulfonylalkyl) benzimidazoles 4. Alternatively, 4 can also be prepared by the reaction of 2 with 1-alkyl/aralkyl-2- (⍺–chloroalkyl) benzimidazole 5 in CH₃CN using triethylbenzylammonium chloride (TEBAC) as PTC. 5 are obtained from 1 in turn, by alkylation in CH₃CN under PTC conditions. |
| Page(s): | 488-491 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(03) [March 2007]
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