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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(02) [February 2007] >
| Title: | A Novel synthesis of nitrofuran containing 1,3,4,5-tetra substituted pyrazoles via 1,3-dipolar addition reaction |
| Authors: | Satheesha Rai N, Balakrishna Kalluraya |
| Keywords: | Sydnones
Acetylinic ketone
Pyrazoles
Dipolar addition
Biological activity |
| Issue Date: | Feb-2007 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.⁸ C07D |
| Abstract: | A hitherto unreported novel series of nitrofuran containing 1,3,4,5-tetra substituted pyrazole derivatives are prepared by the 1,3-dipolar cycloaddition reaction between 1-aryl-3-(5-nitro-2-furyl)propynones 1 with 4-substituted-3-aryl sydnones 2. The structures of these compounds are established by elemental analysis, IR, ¹H NMR and mass Spectral data. The new compounds are also screened for their antibacterial and antifungal activity and most of them showed significant activity. |
| Page(s): | 375-378 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(02) [February 2007]
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