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Title: A Novel synthesis of nitrofuran containing 1,3,4,5-tetra substituted pyrazoles via 1,3-dipolar addition reaction
Authors: Satheesha Rai N, Balakrishna Kalluraya
Keywords: Sydnones;Acetylinic ketone;Pyrazoles;Dipolar addition;Biological activity
Issue Date: Feb-2007
Publisher: CSIR
IPC Code: Int.Cl.⁸ C07D
Abstract: A hitherto unreported novel series of nitrofuran containing 1,3,4,5-tetra substituted pyrazole derivatives are prepared by the 1,3-dipolar cycloaddition reaction between 1-aryl-3-(5-nitro-2-furyl)propynones 1 with 4-substituted-3-aryl sydnones 2. The structures of these compounds are established by elemental analysis, IR, ¹H NMR and mass Spectral data. The new compounds are also screened for their antibacterial and antifungal activity and most of them showed significant activity.
Page(s): 375-378
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.46B(02) [February 2007]

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