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IJC-B Vol.46B [2007] >
IJC-B Vol.46B(02) [February 2007] >


Title: A Novel synthesis of nitrofuran containing 1,3,4,5-tetra substituted pyrazoles via 1,3-dipolar addition reaction
Authors: Satheesha Rai N, Balakrishna Kalluraya
Keywords: Sydnones
Acetylinic ketone
Pyrazoles
Dipolar addition
Biological activity
Issue Date: Feb-2007
Publisher: CSIR
IPC CodeInt.Cl.⁸ C07D
Abstract: A hitherto unreported novel series of nitrofuran containing 1,3,4,5-tetra substituted pyrazole derivatives are prepared by the 1,3-dipolar cycloaddition reaction between 1-aryl-3-(5-nitro-2-furyl)propynones 1 with 4-substituted-3-aryl sydnones 2. The structures of these compounds are established by elemental analysis, IR, ¹H NMR and mass Spectral data. The new compounds are also screened for their antibacterial and antifungal activity and most of them showed significant activity.
Page(s): 375-378
ISSN: 0376-4699
Source:IJC-B Vol.46B(02) [February 2007]

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