Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSanthosh, L-
dc.contributor.authorKrishnamurthy, M-
dc.contributor.authorSureshbabu, Vommina V-
dc.identifier.issn0975-0983(Online); 0376-4699(Print)-
dc.description.abstractSynthesis of enantiomerically pure α-isocyano esters has been described starting from α-amino acids. The end products are obtained in good yields by dehydration of N-formyl amino acid esters using PPh3/I2 in the presence of NMM in CH2Cl2 at −15 to 0°C within 1 h. The protocol has been further extended to obtain N-Fmoc-β-amino alkylisonitiles 4j-l, which were isolated as stable solids, purified and fully characterized by mass, 1H and 13C NMR analysis.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-B Vol.57B(09) [September 2018]en_US
dc.subjectN-Formyl amino acid estersen_US
dc.subjectα-isocyano estersen_US
dc.subjectN-Fmoc-β-amino alkyl isonitilesen_US
dc.subjectα-amino acidsen_US
dc.titleA convenient synthesis of enantiomerically pure α-isocyano esters and Nβ-Fmoc-amino alkyl isonitriles derived from α-amino acids employing PPh3/I2 under mild conditionsen_US
Appears in Collections:IJC-B Vol.57B(09) [September 2018]

Files in This Item:
File Description SizeFormat 
IJCB 57B(9) 1203-1207.pdf262.54 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.