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Title: Synthesis and anti-microbial screening of N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(arylphenyl)acetamide
Authors: Shukla, Maharshi B
Mahyavanshi, Jyotindra B
Joshi, Prakash J
Keywords: 2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile;Acetamide;Antifungal activity;Antibacterial activity
Issue Date: Sep-2018
Publisher: NISCAIR-CSIR, India
Abstract: Reactions of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile with 2-chloro-N-(aryl)-acetamides give N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(arylphenyl)acetamide. The structure of novel compounds has been established on the basis of their substituted N-chloro aryl acetamide derivatives. All the compounds have been characterized by FT-IR, 1H NMR and mass spectroscopy. These new compounds have been evaluated for their in vitro antibacterial and antifungal activity.
Page(s): 1222-1227
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.57B(09) [September 2018]

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