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|Title:||Synthesis, characterization and antimicrobial activity of some ethyl-2-(4-(2-isonicotinoylhydrazinyl)-6-(arylamino)-1,3,5-triazin-2-ylamino)-4- methylthiazole-5-carboxylates|
|Authors:||Desai, N C|
Makwana, Atul H
Senta, R D
|Abstract:||In the present study, isoniazid, thiazole and 1,3,5-triazine moieties have been clubbed in one frame work to synthesize a new series of ethyl 2-(4-(2-isonicotinoylhydrazinyl)-6-(arylamino)-1,3,5-triazin-2-ylamino)-4-methylthiazole-5-carboxylates 3a-n. The newly synthesized compounds have been screened for their in vitro antimicrobial activity. Compounds 3a, 3c, 3d and 3l have exhibited significant antimicrobial activity on several strains of microbes. The structures of the newly synthesized compounds have been elucidated by IR, 1H and 13C NMR, and mass spectral analysis.|
|Appears in Collections:||IJC-B Vol.57B(07) [July 2018]|
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