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IJEB Vol.46(04) [April 2008] >


Title: Beneficial effects of Lagenaria siceraria (Mol.) Standley fruit epicarp in animal models
Authors: Deshpande, J R
Choudhari, A A
Mishra, M R
Meghre, V S
Wadodkar, S G
Dorle, A K
Keywords: Antioxidant
Antihyperlipidemic
Antihyperglycemic
Cardiotonic
Hepatoprotective
Immunomodulatory
Lagenaria siceraria
Issue Date: Apr-2008
Publisher: CSIR
Abstract:  Lagenaria siceraria (Mol.) Standley fruit (bottle gourd), a commonly used vegetable in India is described as cardiotonic and as a general tonic in Ayurveda. Keeping in view the presence of free radical scavenging activity in L. siceraria and involvement of free radicals in the development of various disorders, present studies were designed to evaluate the ethanolic extract of L. siceraria fruit against the disorders where free radicals play a major role in pathogenesis. The extract was found effective as hepatoprotective, antioxidant, antihyperglycemic, immunomodulatory, antihyperlipidemic and cardiotonic agent. The results showed that the radical scavenging capacity of L. siceraria fruit may be responsible for various biological activities studied.
Page(s): 234-242
ISSN: 0019-5189
Source:IJEB Vol.46(04) [April 2008]

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