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|Title:||Immunomodulatory effects of edible Chinese black ant, Polyrhachis vicina Roger extract by using supercritical CO2|
|Keywords:||Food supplement;Immunological function;Insect utilization;Supercritical CO2 fluid extraction;Traditional medicine|
|Abstract:||The Chinese black ant, Polyrhachis vicina Roger has been used as a traditional Chinese medicine and nutritional ingredient. In order to take full advantage of P. vicina resources, the supercritical fluid CO2 (SF-CO2) P. vicina extraction on the immune systems of mice was carried out. The effects of SF-CO2 P. vicina extraction on spleen index, thymus index and carbon expurgation experiments of mice, indicated that P. vicina extraction did not affect visceral index, but enhanced observably carbon expurgatory index, phagocytic index.P. vicina extraction could stimulate response of delayed hypersensitivity. The proliferation of ConA induced mitogenic reponse for spleen lymphocyte was also increased. The amount of hemolytic antibody in mice serum increased compared with those of the control group mice. The half of hemolysis values, acid phosphatase and alkaline phosphatase activity in serum of treated mice increased compared to the control group. Furthermore, serum NO content in all treatment groups was higher than that of the control group. Our findings suggest that SF-CO2 P. vicina extraction has potential as a health food supplement.|
|ISSN:||0975-1009 (Online); 0019-5189 (Print)|
|Appears in Collections:||IJEB Vol.56(06) [June 2018]|
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