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IJEB Vol.46(02) [February 2008] >


Title: Anti-microfilarial activity of methanolic extract of Vitex negundo and Aegle marmelos and their phytochemical analysis
Authors: Sahare, K N
Anandhraman, V
Meshram, V G
Meshram, S U
Reddy, M V R
Tumane, P M
Goswami, K
Keywords: Aegle marmelos
Antifilarial activity
Microfilariae
Phytochemicals
Ricinus communis
Vitex negundo
Issue Date: Feb-2008
Publisher: CSIR
Abstract: In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr. were explored for possible antifilarial effect against Brugia malayi microfilariae. It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration showed complete loss of motility of microfilariae after 48 hr of incubation. Thin layer chromatography of the extracts revealed the presence of alkaloids, saponin and flavonoids in the roots of Vitex negundo L. and coumarin in the leaves of Aegle marmelos Corr.
Page(s): 128-131
ISSN: 0019-5189
Source:IJEB Vol.46(02) [February 2008]

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