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IJEB Vol.46(02) [February 2008] >


Title: In vitro antiviral activity of plant extracts on goatpox virus replication
Authors: Bhanuprakash, V
Hosamani, M
Balamurugan, V
Gandhale, P
Naresh, Ram
Swarup, D
Singh, R K
Keywords: Acacia arabica
Antiviral activity
Eugenia jambolana
Goatpox virus
Issue Date: Feb-2008
Publisher: CSIR
Abstract: Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93±0.38 and 1999.73±0.50 mg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. Results indicated that the extract of Acacia arabica and Eugenia jambolana leaves inhibited GTPV replication in vitro.
Page(s): 120-127
ISSN: 0019-5189
Source:IJEB Vol.46(02) [February 2008]

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