NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.47 [2009] >
IJEB Vol.47(06) [June 2009] >


Title: Potential complications to TB vaccine testing in animal models
Authors: Orme, Ian M
Keywords: Animal model
Foxp3+ cells
Lung necrosis
TB vaccine
T cell
Issue Date: Jun-2009
Publisher: CSIR
Abstract: Testing of new vaccines in animal models has certain advantages and disadvantages. As we better understand the complexity of the immune response to vaccines, new information may be complicating the assessment of the efficacy of new candidate vaccines. Four possible complications are discussed here, (i) induction of Foxp3+ T cells; (ii) induction of memory T cell subsets; (iii) location of extracellular organisms in lung necrosis; and (iv) protection against isolates of high/extreme immunopathology.
Page(s): 440-444
ISSN: 0019-5189
Source:IJEB Vol.47(06) [June 2009]

Files in This Item:

File Description SizeFormat
IJEB 47(6) 440-444.pdf1.3 MBAdobe PDFView/Open
 Current Page Visits: 511 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 584901 since 06-Feb-2009  Last updated on 17-Sep-2014Webmaster: nopr@niscair.res.in