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Title: The low dose of drumsticks (Moringa oleifera L.) seed powder ameliorates blood cholesterol in hypercholesterolemic male rat
Authors: Rabey, Haddad A El
Khan, Jalaluddin A
Almutairi, Fahad M
Elbakry, Mohamed A
Keywords: Hypercholesterolemia;Liver;Moringa;Pathology;Triglyceride
Issue Date: Dec-2017
Publisher: NISCAIR-CSIR, India
Abstract: This study was focused on testing the hypolipidemic effect of two low doses of moringa seed powder on hypercholesterolemic male rats. Twenty four male rats weighing 180-200 gm were divided into four groups. Rats (n = 6/group) were fed a high-lipid diet supplemented (positive controls) or not (negative controls) with cholesterol at 2%; in experimental groups, the hypercholesterolemic diet was supplemented with Moringa oleifera seed powder 50 or 100 mg/kg body wt. Plasma lipids, hepatic enzymes, cardiac enzymes and liver histology were evaluated. The results indicate that dietary supplementation of moringa seed powder is anti-hypercholesterolemic and hepatoprotective. The tested low doses of moringa seed understudy on hypercholesterolemic male rats ameliorated the lipid profile, improved liver function, heart enzymes and restored the liver tissues to normal.
Page(s): 306-313
ISSN: 0975-0959 (Online); 0301-1208 (Print)
Appears in Collections:IJBB Vol.54(6) [December 2017]

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