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|Title:||Synthesis and antimicrobial activity of naphtho-[1,2-e][1,3]oxazines linked benzimidazole|
|Keywords:||2-(1H-Benzo[d]imidazol-2-yl)-2,3-dihydro-1-aryl-1H-naphtho[1,2-e][1,3]oxazines;One-pot synthesis;Three- component reaction;Antimicrobial activity|
|Abstract:||A new series of 2-(1H-benzo[d]imidazol-2-yl)-2,3-dihydro-1-aryl-1H-naphtho-[1,2-e][1,3]oxazines have been accomplished by a green protocol utilizing an efficient atom economic three component coupling reaction. The reaction of 2-amino benzimidazole, aromatic aldehydes with β-naphthol on oil bath has produced the corresponding 1-(1H-benzo[d]imidazol-2-yl amino) phenyl (methyl) naphthalene-2-ols, which have been then cyclized to the title products by treatment with formaldehyde. The title compounds have been screened for their antimicrobial activity. Some of the compounds show promising antimicrobial activity.|
|Appears in Collections:||IJC-B Vol.56B(11) [November 2017]|
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