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Title: Clinical evaluation of efficacy and safety of appetizer syrup as appetite stimulant in children with non-pathogenic anorexia
Authors: Sastry, JLN
Tathed, PS
Rai, Rajiv K
Sasibhushan, V
Keywords: Non-pathogenic anorexia;Appetite stimulant;Children;Herbal;Ayurveda
Issue Date: Oct-2017
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl.8: A01D 7/03, A23L 29/30, A23L 33/125, A61K 36/00
Abstract: Anorexia, i.e., lack of desire to eat or loss of appetite is a common cause of parental concern in pre-school and school-going children. Many herbs and herbal formulations have been traditionally used in India as ‘appetizers’ in children with non-pathological anorexia and over 100 phyto-constituents are claimed to have appetite-stimulant effects, though efficacy and safety of many of these formulations needs to be evaluated with well-controlled clinical trials. Appetizer syrup (Mfd: Dabur India Limited) is an Ayurvedic polyherbal formulation proposed to stimulate appetite in children with non-pathogenic anorexia. It comprises herbs such as Kismis (Vitis vinifera L.), Pipalli (Piper longum L.), Anar (Punica granatum L.), Amla (Emblica officinalis Gaertn), etc., that are traditionally known to be useful in digestive impairment and are documented to possess appetite stimulant and strength promoting properties. Present trial was a double-blind, randomized, placebo-controlled parallel group clinical study to evaluate the efficacy and safety of Appetizer Syrup in children with non-pathogenic anorexia. Results were assessed from baseline to study completion on basis of the appetite stimulating effects of the formulation and the benefits secondary to appetite stimulation like changes in anthropometric measurements and academic performance.
Page(s): 700-705
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.16(4) [October 2017]

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