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Title: Microwave-assisted synthesis of some new biquinoline compounds catalyzed by DMAP and their biological activities
Authors: Nirmal, Jay P
Patel, Manish P
Patel, Ranjan G
Keywords: Biquinoline;DMAP;microwave heating;microbial activity
Issue Date: May-2009
Publisher: CSIR
Abstract: A series of new biquinoline compounds 4a-t have been synthesized by reaction of [(2-chloro-3-quinolyl) methylene]methane-1,1-dicarbonitrile 2a-d and 3-arylamino-5,5-dimethyl-cyclohex-2-en-1-one 3a-e under microwave irradiation catalyzed by 4-(N,N-dimethylamino) pyridine (DMAP). This newer method produces pure product in high yield rapidly. The synthesized compounds 4a-t have been characterized by elemental analysis, IR, NMR and screened for their antifungal and antibacterial activity.
Page(s): 712-717
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.48B(05) [May 2009]

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