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Title: Photo induced synthesis of methyl derivative of cryptosanguinolentine
Authors: Pitchai, P
Mohan, P S
Gengan, R M
Keywords: Microwave;photochemical cyclization;cryptosanguinolentine;iodination
Issue Date: May-2009
Publisher: CSIR
Abstract: A simpler method to synthesize methyl derivative of an alkaloid cryprosanguinolentine is described. 4-Hydroxy-2-methylquinoline is iodized using iodine, potassium iodide and aqueous sodium hydroxide and dehydroxyhalogenated with phosphorous oxychloride. The respective anilinoquinoline is prepared and cyclized by UV irradiation. Upon selective methylation 5,6-dimethyl-5H-indolo[3,2-c]quinoline is produced which is utilized as a DNA intercalating agent.
Page(s): 692-696
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.48B(05) [May 2009]

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