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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(05) [May 2009] >
| Title: | Photo induced synthesis of methyl derivative of cryptosanguinolentine |
| Authors: | Pitchai, P
Mohan, P S
Gengan, R M |
| Keywords: | Microwave
photochemical cyclization
cryptosanguinolentine
iodination |
| Issue Date: | May-2009 |
| Publisher: | CSIR |
| Abstract: | A simpler method to synthesize methyl derivative of an alkaloid cryprosanguinolentine is described. 4-Hydroxy-2-methylquinoline is iodized using iodine, potassium iodide and aqueous sodium hydroxide and dehydroxyhalogenated with phosphorous oxychloride. The respective anilinoquinoline is prepared and cyclized by UV irradiation. Upon selective methylation 5,6-dimethyl-5H-indolo[3,2-c]quinoline is produced which is utilized as a DNA intercalating agent. |
| Page(s): | 692-696 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.48B(05) [May 2009]
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