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NPR Vol.8 [2009] >
NPR Vol.8(2) [March-April 2009] >


Title: Evaluation of protective effects of ethanolic extract of Costus speciosus (Koenig) Sm. rhizomes on carbon tetrachloride induced hepatotoxicity in rats
Authors: Verma, Nitin
Khosa, R L
Keywords: Costus speciosus
Carbon tetrachloride
Ethanolic extract
Hepatoprotective activity
Lipid peroxidation
Issue Date: Apr-2009
Publisher: CSIR
IPC CodeInt. cl.8 — A61K 36/00, A61K 36/906, A61K 125/00, A61P 1/16
Abstract: The hepatoprotective activity of the ethanolic extract of the rhizomes of Costus speciosus (Koenig) Sm. was studied on carbon tetrachloride treated rats. The extract registered a significant fall in the levels of serum glutamyl oxalacetic acid transaminase (SGOT), serum glutamyl pyruvate transaminase (SGPT), alkaline phosphatase (ALKP), serum bilirubin (SBLN) and liver inflammation supported by histopathological studies on liver, thus exhibited a significant hepatoprotective activity.
Page(s): 123-126
ISSN: 0972-592X
Source:NPR Vol.8(2) [March-April 2009]

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