NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(02) [February 2007] >


Title: Fate of Embelin in Pippalyadi Yoga, an Ayurvedic oral contraceptive: Structure of Embelin-borax complex and evaluation of anti-fertility activity
Authors: Singh, Inder Pal
Bharate, Sandip B
Singh, Anubha
Bhutani, Kamlesh K
Keywords: Pippalyadi Yoga
Embelin
Piperine
Borax
Embelia ribes
Piper longum
Issue Date: Feb-2007
Publisher: CSIR
IPC CodeInt.Cl.⁸ A61K
Abstract: In the present communication, is reported the existence of embelin 1 as embelin-borax complex 3 in a stoichiometry of 1:2 in an Ayurvedic formulation Pippalyadi Yoga. The structure of the complex is established on the basis of spectral data and it is concluded that both the phenolic oxygens as well as carbonyl groups of embelin are involved in complex formation. Embelin-borax complex is stable under basic conditions; however, it is sensitive to acidic conditions and breaks up to yield embelin and borax on treatment with mild acids. Anti-fertility activity of formulation and individual constituents was evaluated at cellular and hormonal level in Sprague Dawley female albino rats. Pippalyadi Yoga showed better activity than any of the individual constituents in the formulation including the complex.
Page(s): 320-325
ISSN: 0367-4699
Source:IJC-B Vol.46B(02) [February 2007]

Files in This Item:

File Description SizeFormat
IJCB 46B(2) (2007) 320-325.pdf114.62 kBAdobe PDFView/Open
 Current Page Visits: 876 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 586377 since 06-Feb-2009  Last updated on 18-Sep-2014Webmaster: nopr@niscair.res.in