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IJC-B Vol.46B(02) [February 2007] >


Title: The effect of Glu→Asp substitution on a 3₁₀ type fold in The effect of Glu→Asp substitution on a 3₁₀ type fold in Boc-(D)-Glu₁-Ala₂-Gly₃-Lys₄-NHMe
Authors: Bobade, V D
Mhaske, P C
Gaikwad, N D
Keywords: D-Amino acid
3₁₀-helical conformation
Helix design
Salt bridge
β-turns
Issue Date: Feb-2007
Publisher: CSIR
IPC CodeInt.Cl.⁸C07C
Abstract: The solution conformation of the peptide Boc-(D)-Asp₁-Ala₂-Gly₃-Lys₄-NHMe based on NMR studies is compared with its (D)-Glu₁ analog reported earlier. Results establish that (D)-Asp analog is devoid of the salt bridge and is a complex ensemble of consecutive folds.
Page(s): 308-313
ISSN: 0367-4699
Source:IJC-B Vol.46B(02) [February 2007]

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