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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(02) [February 2007] >
| Title: | The effect of Glu→Asp substitution on a 3₁₀ type fold in The effect of Glu→Asp substitution on a 3₁₀ type fold in Boc-(D)-Glu₁-Ala₂-Gly₃-Lys₄-NHMe |
| Authors: | Bobade, V D
Mhaske, P C
Gaikwad, N D |
| Keywords: | D-Amino acid
3₁₀-helical conformation
Helix design
Salt bridge
β-turns |
| Issue Date: | Feb-2007 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.⁸C07C |
| Abstract: | The solution conformation of the peptide Boc-(D)-Asp₁-Ala₂-Gly₃-Lys₄-NHMe based on NMR studies is compared with its (D)-Glu₁ analog reported earlier. Results establish that (D)-Asp analog is devoid of the salt bridge and is a complex ensemble of consecutive folds. |
| Page(s): | 308-313 |
| ISSN: | 0367-4699 |
| Source: | IJC-B Vol.46B(02) [February 2007]
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