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IJC-B Vol.48B [2009] >
IJC-B Vol.48B(04) [April 2009] >


Title: N-Desmethyltriptans: One pot efficient synthesis of N-methyl-2-[5-[substituted-1H-indole-3-yl]ethanamines
Authors: Mittapelli, Vasantha
Ray, Purna Chandra
Chauhan, Yogendra Kumar
Datta, Debashish
Keywords: N-Desmethyltriptans
ethanamines
migraine
meta­bolites
Issue Date: Apr-2009
Publisher: CSIR
Abstract: A straightforward and highly improved method to synthesize N-methyl-2-[5-[substituted-1H-indole-3-yl]ethanamines 4-6, which are the metabolites of tryptans 1-3, is reported. The significance of the process is its simplicity and efficiency in isolating the N-desmethyltriptans derivatives as a free base.
Page(s): 590-594
ISSN: 0376-4699
Source:IJC-B Vol.48B(04) [April 2009]

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