Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/3876
Title: <i style="">N</i>-Desmethyltriptans: One pot efficient synthesis of <i>N</i>-methyl-2-[5-[substituted-1<i>H</i>-indole-3-yl]ethanamines<i style=""> </i>
Authors: Mittapelli, Vasantha
Ray, Purna Chandra
Chauhan, Yogendra Kumar
Datta, Debashish
Keywords: <i style="">N</i>-Desmethyltriptans
ethanamines
migraine
meta­bolites
Issue Date: Apr-2009
Publisher: CSIR
Abstract: A straightforward and highly improved method to synthesize N-methyl-2-[5-[substituted-1H-indole-3-yl]ethanamines <b style="">4-6</b>, which are the metabolites of tryptans <b>1-3</b>, is reported<b>. </b>The significance of the process is its simplicity and efficiency in isolating the N-desmethyltriptans derivatives as a free base.
Description: 590-594
URI: http://hdl.handle.net/123456789/3876
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.48B(04) [April 2009]

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