Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/3875
Title: Conformational analysis of some <i>N</i>-hydroxypiperidin-4-one oximes
Authors: Baskar, G
Gopalakrishnan, M
Jabaraj, J Winfred
Keywords: <sup>1</sup>H NMR
<smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="metricconverter"> <sup>13</sup>C NMR</smarttagtype>
NOESY
conformation and N-hydroxypiperidone oximes
Issue Date: Apr-2009
Publisher: CSIR
Abstract: Analysis of the spectral data (<sup>1</sup>H NMR and<sup>13</sup>C NMR) indicates that out of ten <i>N</i>-hydroxypiperidin-4-one oximes <b>3a-j</b>, the compounds <b>3b</b> and <b>3c</b> exist predominantly in chair conformation with the aryl and alkyl substituents in the equatorial positions, whereas the compounds <b>3d-j</b> exist in boat conformation. The introduction of an oxime group at C-4 causes a flattening of the ring about C(5)-C(6) bond. The NOESY spectrum (Nuclear Overhauser effect) recorded for the compound <b>3d</b> further supports the assigned boat conformation.
Description: 580-584
URI: http://hdl.handle.net/123456789/3875
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.48B(04) [April 2009]

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