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Title: Synthesis of an amino moiety in trovafloxacin by using an in-expensive amidine base, <i style="">N,N</i>-diethylacetamidine
Authors: Madhusudhan, G
Balraju, V
Rajesh, T
Narayana, B Venkata
Reddy, R Naveen
Keywords: <i style="">N,N</i>-Diethylacetamidine
bicyclic hetero compounds
antibacterial agent
Issue Date: Apr-2009
Publisher: CSIR
Abstract: <smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="metricconverter"> The simple and in-expensive amidine base, <i style="">N,N</i>-diethylacetamidine, has been prepared and utilized in the construction of bicyclic hetero compound, <b style="">4</b> and employed for further reduction of amidic carbonyl groups of <b style="">4</b> by using NaBH<sub>4</sub>/I<sub>2</sub>-THF condition which is an efficient and commercially viable method to prepare <b style="">5</b> towards the synthesis of amino moiety <b style="">1</b>, in Trovafloxacin <b style="">2 </b>an antibacterial agent. </smarttagtype>
Description: 569-573
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.48B(04) [April 2009]

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