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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.47B [2008] >
IJC-B Vol.47B(01) [January 2008] >
| Title: | Synthesis of some new 2-(4-alkylthiophenoxy)-4-substituted-1, 3-thiazoles as possible anti-inflammatory and antimicrobial agents |
| Authors: | T, Karabasanagouda
Adhikari, Airody Vasudeva
Dhanwad, Ramgopal
Parameshwarappa, G |
| Keywords: | 2-{[4-(Alkylthio)phenoxy]methyl}-4-aryl-1
3-thia-zoles
4-(substitutedmethyl)-2-{[4-(alkylthio)phenoxy]meth-yl}- 1
3 thiazoles
anti-inflammatory activity
antibacterial
antifungal screening |
| Issue Date: | Jan-2008 |
| Publisher: | CSIR |
| Abstract: | A series of new 2-{[4-(alkylthio)phenoxy]methyl}-4-substi¬tuted-1,3-thiazoles 4a-q, 6a-j have been synthesized from ethyl [4-(alkylthio)phenoxy]acetates 1a,b through multi-step reaction sequence. The structures of new compounds have been esta¬blished on the basis of their elemental analysis and IR, 1H and 13C NMR and mass spectral data. Selected title compounds have been evaluated for anti-inflammatory activity and in vitro antibacterial testing against two pathogenic strains and antifungal screening against two fungi. |
| Page(s): | 144-152 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.47B(01) [January 2008]
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