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Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
NPR Vol.8 [2009] >
NPR Vol.8(1) [January-February 2009] >
| Title: | Changes in some biochemical parameters in the liver and muscle of Colisa fasciatus due to toxicity of ethanolic extract of Nerium indicum Mill. (Lal Kaner) latex |
| Authors: | Tiwari, Sudhanshu
Singh, Ajay |
| Keywords: | Biochemical changes
Colisa fasciatus
Freshwater weed fish
Lal Kaner
Latex
Nerium indicum
Piscicidal activity |
| Issue Date: | Feb-2009 |
| Publisher: | CSIR |
| IPC Code: | Int. cl.8— A61K 36/24, A01N 65/00 |
| Abstract: | Present study deals with piscicidal, toxicological and biochemical effects of ethanolic
extract of Nerium indicum Mill. (Lal Kaner) latex against freshwater weed fish Colisa
fasciatus. There was a significant (P<0.05) negative correlation between LC values and exposure
periods i.e. LC50 values decreased from 14.05mg/l (24h) to 5.52mg/l (96h). Sub-lethal exposure
of ethanolic latex extract for 24h and 96h caused significant (P<0.05) time and dose dependent
alterations in the levels of total protein, total free amino acid, nucleic acid, glycogen, pyruvate,
lactate and also in the activity of enzyme protease, alanine aminotransferase, aspartate
aminotransferase, acetylcholinesterase, lactic dehydrogenase, succinic dehydrogenase and
cytochrome oxidase in liver and muscle tissues of fish. Withdrawal experiments shows, their
biochemical effects are reversible in action. Thus, N. indicum latex extract mainly suppress
energy production and shifts fish respiration towards the anaerobic segment. |
| Page(s): | 48-54 |
| ISSN: | 0972-592X |
| Source: | NPR Vol.8(1) [January-February 2009]
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